Transporters相关论文
In analyses of protein families that may serve as drug targets,membrane-associated G-protein-coupled receptors(GPCRs)dom......
Toxic metals and metalloids:Uptake,transport,detoxification,phytoremediation,and crop improvement fo
Agricultural soils are under threat of toxic metal/metalloid contamination from anthropogenic activities,leading to exce......
Tolvaptan induces cholestasis and hepatoxicity through altered expression and function of transporte
Tolvaptan is an orally active vasopressin V2 receptor antagonist clinically used in the treatment of hyponatremia.Recent......
Effect of cholecystectomy on bile acids, enzymes and transporters in mice:Implications for pharmacok
Cholecystectomy is a traditional and effective therapeutic tool for hepatobiliary diseases whose morbidity has increased......
Quantitative analysis to reveal membrane proteins mediated hypersaline sensitivity and adaptation in
Soil salinization is an important worldwide environmental problem, especially in semi-arid and arid regions.Xinjiang (Ch......
Lipid dysmetabolism is one of the main features of diabetes mellitus and manifests by dyslipidemia as well as the ectopi......
Quantitative analysis to reveal membrane proteins mediated hypersaline sensitivity and adaptation in
Soil salinization is an important worldwide environmental problem,especially in semi-arid and arid regions.Xinjiang ......
Monocarboxylate transporters(MCTs), which carry monocarboxylates such as lactate across biological membranes, have been ......
AIM: To examine renal expression of organic anion transporter 5(Oat5) and sodium-dicarboxylate cotransporter 1(Na DC1), ......
Asymmetric-dimethylarginine(ADMA) competes with L-arginine for each of the three isoforms of nitric oxide synthase:endot......
Nitrogen use efficiency (NUE) was very low in China and a loss of as much as 70% of the applied nitrogen fertilizers was......
IntroductionRenalglomerularlesionofhumanandexperimentaldiabetesmellitusischaracter-izedbyglomerularhypertrophyandexces-s......
AIM To investigate the pharmacological effect of Tong XieYao Fang(TXYF) formula, a Chinese herbal formula, on Diarrhea-p......
Aim:To assess the effects and mechanisms of the action of resistin on basal andinsulin-stimulated glucose uptake in rat......
近年来,对体内药物转运体的研究取得了重大进展,越来越多的转运体被发现及研究,其对药物的跨膜转运,具有重要的意义。各种转运体包......
High glucose decreases the expression of ATP-binding cassette transporter G1 in human vascular smoot
Objective:ATP-binding cassette transporters(ABC)A1 and G1 play an important role in mediating cholesterol efflux and pre......
A monosaccharide transporter is localized to sieve plate and plasmodesmal channel in developing appl
Two major classes of plant sugar transporters, sucrose and monosaccharide transporters, may be localized to tonoplast or......
Disease control by regulation of P-glycoprotein on lymphocytes in patients with rheumatoid arthritis
The main purpose of treatment of rheumatoid arthritis(RA) with disease modifying antirheumatic drugs(DMARDs) is to contr......
The 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors, statins, are widely used in the primary and secondary prev......
Pharmacogenetics of type 2 diabetes mellitus: An example of success in clinical and translational me
The pharmacological interventions currently available to control type 2 diabetes mellitus(T2DM) show a wide interindivid......
Aim Hydrogen(dihydrogen,H2) is an effective antioxidant to reduce oxidative stress and oxidative stress is implicated in......
Since the early reports nearly a decade ago, proton-pump inhibitor-induced hypomagnesemia(PPIH) has become a well-recogn......
Potential Herb-Drug Interaction in the Prevention of Cardiovascular Diseases during Integrated Tradi
The combination of herbs and drugs is one of the most important approaches in the prevention and treatment of diseases i......
AIM: To investigate the effect of 1-methyl-4-phenylpyridinium (MPP+) on the glutamate uptake into cultured C6 glioma ce......
Type 2 diabetes mellitus(T2DM) is a silent progressive polygenic metabolic disorder resulting from ineffective insulin c......
锚蛋白家族是重要的整合蛋白,参与心血管系统中离子通道、跨膜蛋白在细胞膜上的固定及适当表达和功能维持.锚蛋白通路的缺陷可以导......
目的研究茵栀黄水提物(YZH)对α-异硫氰酸酯(ANIT)诱导的胆汁淤积小鼠的作用。方法小鼠按照体重随机分为6组:正常组、模型组、3个......
Environmental pollution is one of the major problems for human health. Toxic heavy metals are normally present as soil c......
The behavior of nano-confined water is expected to be fundamentally different from the behavior of bulk water.At the nan......
Background The diagnosis of Parkinson’s disease is presently based on non-specific symptoms. However, radionuclide dop......
Comparable investigation in dopamine transporters with ~(99m)Tc-TRODAT-1 and ~(131)I-FP-CIT SPECT in
Dopamine transporter (DAT) mediates the regulation of dopaminergic function. Two agents of TRODAT-1 and FP-CIT were obse......
Carbohydrates are an important component of the diet. The carbohydrates that we ingest range from simple monosaccharides......
BACKGROUND: Radio-imaging has been used in neurological diagnosis,in particular for extrapyramidal disease.Moreover,it h......
Vesicle-based traffi cking of hepatocellular transporters involves delivery of the newly-synthesized carriers from the r......
The disposition of most drugs is highly dependent on specialized transporters.OAT1 and OAT3 are two organic anion transp......
This review focuses on current knowledge on hepato-cyte aquaporins(AQPs)and their significance in bile formation and cho......
The canalicular membrane represents the excretory pole of hepatocytes.Bile is an important route of elimination of poten......
Dynamic expression of cerebral cortex and hippocampal glutamate transporters in a rat model of chest
The present study established a rat model of global cerebral ischemia induced by chest compression for six minutes to dy......
Anomalous expression of chloride transporters in the sclerosed hippocampus of mesial temporal lobe e
The Na+-K+-Cl-cotransporter 1 and K+-Cl-cotransporter 2 regulate the levels of intracellular chloride in hippocampal cel......
Obstructive jaundice occurs in patients suffering from cholelithiasis and from neoplasms affecting the pancreas and the ......
阜阳市局 ￡4a 局长——_MINtkMMtgj’＃lnH＄B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
D-galactose has been widely used in aging research because of its efficacy in inducing senescence and accelerating aging......
Targeting brain microvascular endothelial cells: a therapeutic approach to neuroprotection against s
Brain microvascular endothelial cells form the interface between nervous tissue and circulating blood, and regulate cent......
Microarray analysis of PBMC after Plasmodium falciparum infection:molecular insights into disease pa
Objective:To find out host gene expression profiles after malarial infection.Methods:Further time-course microarray anal......
The decrease of connexin43 mediated down-regulation of glutamate transporter1 in spinal astrocytes u
OBJECTIVE Astrocytic gap junctions formed by connexin 43(Cx43) are crucial for intercellular communication between spina......
Comment on “Effect of biofilm formation by clinical isolates of Helicobacter pylori on the efflux-me
Attaran et al[1] have recently shown that decreased susceptibility of established Helicobacter pylori(H. pylori) biofilm......
Interindividual differences in the toxicity and response to anticancer therapies are currently observed in practically a......
真核生物高亲和力谷氨酸转运体(excitatory amino acid transporters,EAATs)分为GLAST(EAAT1)、GLT-1(EAAT2)、EAAC1(EAAT3)、EAAT......
